QUANTITATIVE TRAIT LOCI (QTL) STUDY IDENTIFIES NOVEL GENOMIC REGIONS ASSOCIATED TO CHIARI-LIKE MALFORMATION IN GRIFFON BRUXELLOIS DOGS.

Quantitative trait loci (QTL) study identifies novel genomic regions associated to Chiari-like malformation in Griffon Bruxellois dogs.

Chiari-like malformation (CM) is a developmental abnormality of the craniocervical junction that is common in the Griffon Bruxellois (GB) breed with an estimated prevalence of 65%.This disease is characterized by overcrowding of the neural parenchyma at the craniocervical junction and disturbance of cerebrospinal fluid (CSF) flow.The most common cl

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Hierarchical two-step floating catchment area (2SFCA) method: measuring the spatial accessibility to hierarchical healthcare facilities in Shenzhen, China

Abstract Background Spatial accessibility to healthcare facilities has drawn much attention in health geography.In China, central and local governments have aimed to develop a well-organized hierarchical system of healthcare facilities in recent years.However, few studies have focused on the measurement of healthcare accessibility in a hierarchical

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